University of Ljubljana, Faculty of Electrical Engineering, Ljubljana, Slovenia
HEAD ASSIST. PROF. MOJCA PAVLIN, PhD
Group for nano and biotechnological applications is a young interdisciplinary research group at the Faculty of Electrical Engineering University of Ljubljana and Institute of Biophysics, Faculty of Medicine, University of Ljubljana. The group includes physicists, biologists and biochemists as well as several undergraduate and graduate students from different areas of life sciences and technology. Collaboration with complementary research groups in Slovenia and abroad enables translation of the research results into clinical and industrial setting.
The research work of the Group for nano and biotechnological applications includes different areas of biomedicine, biotechnology and nanobiotechnology related to drug delivery methods and cancer research. The main areas of research are:
development and characterization of magnetic nanoparticles; development of new formulations of magnetic nanoparticles (NPs) for biomedical applications (drug delivery, cell labeling), analysis of NP uptake mechanisms and cytotoxicity, assessment of potential nanotoxicity and immunogenicy, the outlook on nanotechnology and nano safety,
in vitro research of cellular metabolic pathways of cancer cells in relation to Warburg effect and analysis of pharmacological modulation of cell metabolism for therapy of cancer.
biotechnology applications with electroporation method – gene electrotransfer in vitro and in 3D in vitro tissue models, delivery of small molecules, proteins, DNA and short RNAi into various mammalian, tumour and primary human cells.